Anti-PRMT3 Antibody

Raised in rabbits against human protein arginine methyltransferase 3, this unconjugated polyclonal IgG reagent from Antibodies.com detects PRMT3 in Western blot and immunohistochemistry workflows. The 200 µl size provides ample material for multiple gels and staining runs, with reactivity confirmed against human and mouse samples. Each lot is affinity-purified from whole antiserum and validated on positive-control lysates to confirm recognition of the target methyltransferase rather than related PRMT family members.

PRMT3 functions as a predominantly cytoplasmic type I arginine methyltransferase that asymmetrically dimethylates arginine residues on substrates including ribosomal proteins and selected RNA-binding partners. Researchers studying post-translational modification, ribosome biogenesis, or cellular stress signaling use this antibody to map expression patterns across cell lines and FFPE tissue sections. For handling, aliquot the antiserum upon arrival to limit freeze-thaw cycles, keep the working aliquot refrigerated at 4 degrees C with sodium azide preservative, and store the stock frozen at -20 degrees C or below for long-term stability.