Anti-PRMT3 Antibody

This polyclonal reagent from Antibodies.com targets PRMT3, a type I protein arginine methyltransferase that catalyzes asymmetric dimethylation of arginine residues on substrates such as the ribosomal protein rpS2. The antibody is raised in rabbit hosts and supplied as an unconjugated IgG preparation, leaving detection chemistry to the investigator's chosen secondary system.

Validated for Western blot and immunohistochemistry, the antibody recognizes endogenous PRMT3 in human and mouse samples. Researchers apply it to studies of arginine methylation, ribosome biogenesis, and translational control under basal and cellular stress conditions. Reported uses include profiling PRMT3 expression in hepatic tissue, neural sections, and tumor-derived specimens, where altered methylation activity has been linked to specific cellular phenotypes and disease pathways.

Each vial contains 100 µl of antibody, sufficient for multiple membrane and slide-based experiments. Store the product refrigerated and protect from light; aliquot working volumes to limit freeze-thaw cycles during longitudinal studies. As a polyclonal reagent, the preparation contains immunoglobulins that recognize multiple epitopes on PRMT3, which can improve signal when individual epitopes are obscured by post-translational modification within the target protein.