Anti-PRMT2 Antibody

This unconjugated polyclonal antibody from Antibodies.com targets PRMT2 (Protein Arginine Methyltransferase 2), a type I arginine methyltransferase involved in transcriptional regulation, nuclear receptor signaling, and RNA processing pathways. The reagent is raised in rabbit and validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) applications on human samples, supporting studies of PRMT2 function in cancer biology, estrogen receptor signaling, and metabolic disease models.

The antibody is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, delivered as 100 µl of liquid ready for dilution. Standard handling calls for aliquoting upon receipt, storage at -20 °C for long-term use, and protection from light, with working aliquots kept refrigerated to preserve binding activity across limited freeze-thaw cycles.

As a polyclonal reagent, the antibody recognizes multiple epitopes across the PRMT2 protein, producing stronger signal in denatured western blot workflows and consistent staining in fixed tissue sections. Researchers examining PRMT2's contributions to breast cancer progression, androgen receptor signaling, or NF-κB pathway modulation can apply this reagent to both cell culture lysates and archival tissue specimens. The unconjugated format also permits flexible secondary antibody pairing for multiplex fluorescence or chromogenic detection setups.