Anti-PRMT1 Antibody

PRMT1 (Protein Arginine Methyltransferase 1) acts as the major type I arginine methyltransferase in mammalian cells, and this unconjugated Mouse monoclonal reagent from Antibodies.com enables its detection by Western Blot (WB) in Human samples. The 100 µl purified preparation is supplied in 0.1M Tris-Glycine buffer (pH 7.4) containing 150 mM NaCl, 0.2% sodium azide, and 50% glycerol.

The antibody recognizes PRMT1, which catalyzes methylation of arginine residues on histone H4 (Arg3) and a broad spectrum of non-histone substrates, regulating gene transcription, pre-mRNA splicing, signal transduction, and the DNA damage response. Altered PRMT1 expression has been linked to acute myeloid leukemia, breast carcinoma, and several inflammatory and metabolic disease models, supporting its relevance across oncology, epigenetics, and cell biology research.

For handling, store the vial refrigerated and protect from light; aliquot upon first use and avoid repeated freeze-thaw cycles to preserve antibody activity. The monoclonal format ensures lot-to-lot consistency and defined epitope specificity for reproducible detection of endogenous PRMT1 in cell lysates and tissue homogenates, intended for research use only.