Anti-PRKCG Antibody

Protein kinase C gamma (PRKCG) is a calcium- and diacylglycerol-dependent serine/threonine kinase expressed predominantly in neurons of the central nervous system. This unconjugated rabbit polyclonal antibody from Antibodies.com recognizes PRKCG and is validated for western blot detection in human, rat, and mouse samples. Supplied at 1 mg/ml in phosphate buffered saline (pH ~7.3) with 0.05% sodium azide, the reagent is provided in a vial containing 100 µl of antibody. PRKCG contributes to intracellular signaling, synaptic plasticity, and cerebellar Purkinje cell function, and aberrant kinase activity has been associated with spinocerebellar ataxia type 14 as well as with certain malignancies studied in oncology research. The antibody is used for immunoblotting of full-length PRKCG in cell and tissue lysates to investigate kinase regulation, neuronal signaling pathways, and neurodegenerative disease mechanisms. Aliquot upon receipt and store refrigerated; protect from repeated freeze-thaw cycles to preserve activity.