Anti-PRKAB2 Antibody

Raised in rabbit against the AMPK beta-2 subunit, this unconjugated IgG polyclonal reagent from Antibodies.com targets PRKAB2, the non-catalytic beta isoform of AMP-activated protein kinase (AMPK) that helps assemble the heterotrimeric kinase complex and contributes to glycogen-binding activity in metabolically active tissues.

Validated for Western blot on human and mouse samples, the antibody is supplied in a single-use vial of 100 µl unconjugated IgG, suitable for HRP-based workflows using standard secondary reagents. AMPK beta-2 is expressed across many tissues, with notable levels in skeletal muscle, liver, and pancreatic islets where it supports metabolic regulation and cellular energy-sensing.

For storage, aliquot the vial on receipt and freeze at -20 degrees C in working volumes to limit freeze-thaw cycles, and protect from light once thawed. The reagent detects the endogenous ~30 kDa PRKAB2 band in whole-cell lysates, making it a practical tool for studying AMPK complex assembly, glycogen binding, and downstream signaling events in research-use applications.