Anti-PRKAB1 Antibody

PRKAB1 encodes the beta-1 regulatory subunit of AMP-activated protein kinase (AMPK), a heterotrimeric serine/threonine kinase that serves as a master energy sensor in eukaryotic cells. The beta-1 subunit contributes to substrate recognition, heterotrimer stability, and glycogen-binding capacity, and it is required for proper assembly of the alpha/beta/gamma complex within the cytosol and at the membrane. This unconjugated rabbit polyclonal antibody from Antibodies.com specifically detects PRKAB1 and is validated for western blot and immunohistochemistry on human and mouse specimens, supporting research into metabolic regulation, type 2 diabetes, cardiac ischemia, and tumor cell bioenergetics. The IgG reagent is supplied as 200 µl of liquid in a vial and is intended for research use only, where it can be used to probe the approximately 38 kDa PRKAB1 band in lysates and to localize expression in fixed tissue sections.