Anti-PRDX5 Antibody

Peroxiredoxin 5 (PRDX5) is a broadly expressed antioxidant enzyme of the peroxiredoxin family that reduces hydrogen peroxide, organic hydroperoxides, and peroxynitrite, helping cells manage oxidative stress across mitochondrial, peroxisomal, cytosolic, and nuclear compartments. This polyclonal rabbit antibody binds PRDX5 and is validated for Western blot, immunofluorescence, and immunohistochemistry workflows in human, mouse, and rat samples.

Supplied as an unconjugated reagent in a 100 µl vial, it supports research into redox biology, mitochondrial function, inflammation, and cancer cell survival, where altered PRDX5 expression has been linked to tumor progression and chemoresistance. Researchers investigating oxidative damage markers, neurodegenerative disease models, or peroxisomal disorders rely on anti-PRDX5 reagents to map protein localization and abundance in fixed tissues and lysates.

The polyclonal format increases the likelihood of recognizing multiple epitopes on the target, which is useful when studying post-translational modifications or isoform-specific responses. Storage conditions and buffer composition should be confirmed on the accompanying product insert from Antibodies.com before first use, since prolonged freeze-thaw cycles can reduce binding activity in unconjugated polyclonal preparations.