Anti-PRDX4 Antibody

This polyclonal antibody targets PRDX4 (peroxiredoxin-4), a thioredoxin-dependent peroxidase located in the endoplasmic reticulum that scavenges reactive oxygen species and helps maintain redox balance in cells of the secretory pathway. The Antibodies.com reagent is raised in rabbit, supplied as 100 µl of unconjugated antiserum, and validated for Western Blot (WB) and Immunohistochemistry (IHC) workflows. It cross-reacts with Human, Mouse, and Rat samples, supporting comparative studies of oxidative stress responses across species. Researchers examining ER stress, hepatocellular injury, neurodegeneration, and tumor redox biology deploy this reagent to probe expression patterns and post-translational regulation of peroxiredoxin-4. The unconjugated format allows flexible pairing with HRP, biotin, or fluorophore-conjugated secondary reagents depending on the chosen detection platform, and the polyclonal clonality provides broad epitope coverage useful when target conformation or modification state may vary between samples.