Anti-PRDX4 Antibody

Peroxiredoxin-4 (PRDX4) is a 31 kDa thioredoxin-dependent antioxidant enzyme localized primarily to the endoplasmic reticulum, where it neutralizes hydrogen peroxide and other reactive oxygen species generated during disulfide bond formation. This polyclonal antibody from Antibodies.com is provided at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, supplied as a 100 µl aliquot. The unconjugated reagent is validated for Western blot and immunohistochemistry workflows and cross-reacts with human, mouse, and rat samples, supporting comparative studies across standard model organisms. PRDX4 contributes to ER redox balance, inflammatory signaling, and the regulation of oxidative stress, and altered expression has been investigated in hepatocellular carcinoma, lung adenocarcinoma, and certain neurodegenerative contexts. For long-term storage, keep the vial frozen at -20 °C in working aliquots to limit freeze-thaw cycles. Intended for research use only.