Anti-PRDX3 Antibody

This rabbit polyclonal antibody from Antibodies.com targets peroxiredoxin 3 (PRDX3), a mitochondrial thioredoxin-dependent peroxidase that scavenges reactive oxygen species generated during oxidative phosphorylation. PRDX3 belongs to the 2-Cys peroxiredoxin family and localizes primarily to the mitochondrial matrix, where it protects cells from oxidative damage and supports redox-sensitive signaling pathways involved in cell survival and apoptosis.

The unconjugated IgG reagent is supplied as 200 µl of polyclonal antisera and is validated for western blot, immunohistochemistry, and flow cytometry applications on human samples. As a research-grade reagent, it is intended for studies of mitochondrial antioxidant defense, oxidative stress responses, and PRDX3 expression in tumor biology, neurodegenerative disease models, and metabolic disorders including type 2 diabetes. The antibody recognizes the human PRDX3 protein, which has been characterized for its role in cancer progression, Parkinson's disease, Alzheimer's disease, and cardiovascular pathology.

This reagent supports laboratory workflows examining mitochondrial reactive oxygen species detoxification, redox regulation, and protein expression profiling across cell culture and tissue specimens.