Anti-PRDX1 Antibody

This unconjugated Rabbit polyclonal antibody from Antibodies.com targets Peroxiredoxin 1 (PRDX1), a thioredoxin-dependent peroxidase that scavenges reactive oxygen species and regulates redox signaling in mammalian cells. The antibody is supplied at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% Glycerol as a cryoprotectant, packaged in a 100 µl vial suitable for routine immunodetection workflows.

Validated for Western blot and immunohistochemistry applications, the reagent recognizes endogenous PRDX1 in Human, Mouse, and Rat samples, supporting comparative studies of oxidative stress responses, inflammatory signaling, and tumor biology. The polyclonal format enables recognition of multiple epitopes across the 22 kDa peroxiredoxin protein, which aids detection of full-length PRDX1 and isoform variants reported in the literature, including truncated forms whose activity is modulated by acetylation.

For handling, store the vial at -20°C in single-use aliquots to limit freeze-thaw cycles and preserve binding affinity. Centrifuge briefly before opening and protect from prolonged light exposure. The glycerol-containing formulation stays liquid at -20°C and resists freeze-thaw damage, supporting consistent performance across repeated western blot and IHC runs. Investigators working on redox homeostasis, hepatocellular carcinoma progression, or inflammatory pathway models will find this reagent informative for tracking PRDX1 expression changes under experimental oxidative challenge.