Anti-PRDX1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets Peroxiredoxin 1 (PRDX1), a ubiquitously expressed antioxidant enzyme that scavenges hydrogen peroxide and organic hydroperoxides while regulating redox-sensitive signaling pathways. The unconjugated IgG reagent is supplied as a 200 µl aliquot and is validated for Western blot (WB) and immunohistochemistry (IHC) workflows on Human and Mouse samples, making it a useful reagent for studies of oxidative stress, inflammation, and tumor biology where PRDX1 expression or post-translational modification is being investigated.

Peroxiredoxin family members serve as both peroxidases and chaperones depending on their oligomeric state and the local redox environment. Researchers commonly use anti-PRDX1 antibodies to probe tissue sections and lysates for altered antioxidant capacity in cancer models, neurodegenerative systems, and immune cell function. Each lot is produced in rabbit hosts using polyclonal preparation, providing broader epitope recognition than monoclonal alternatives, which can be advantageous when studying modified, oxidized, or partially denatured PRDX1.