Anti-PRDM5 Antibody

Offered by Antibodies.com as a 200 µl vial of unconjugated rabbit polyclonal IgG, this reagent is raised against the PR/SET domain zinc finger transcription factor PRDM5 and detects endogenous levels of the target in human, mouse, and rat samples. PRDM5 maps to human chromosome 4q26, contains 16 zinc finger motifs, and functions as a sequence-specific DNA-binding repressor that recruits the histone methyltransferase EHMT2/G9A and class I histone deacetylases such as HDAC1 to its target promoters.

Validated applications include Western blot, immunohistochemistry, and immunofluorescence, with recommended starting dilutions of WB 1:500-1:2000, IHC 1:50-1:200, and IF 1:50-1:200 established on the same product record. Researchers investigating tumor suppressor silencing in breast, ovarian, liver, gastric, and colorectal cancers, hematopoiesis-associated gene regulation, or extracellular matrix targets such as COL4A1 and COL11A1 rely on this antibody to track PRDM5 expression and subcellular localization in prepared lysates and tissue sections.

For continuous use, store at -20°C and avoid repeated freeze-thaw cycles. The unconjugated format allows pairing with a labeled secondary reagent matched to the chosen detection system. For research use only.