Anti-PRC1 Antibody

PRC1 (Protein Regulator of Cytokinesis 1) is a microtubule-associated protein essential for cytokinesis, bundling antiparallel microtubules at the central spindle and midbody during mitosis. Antibodies.com offers this unconjugated rabbit polyclonal reagent raised against the human PRC1 target, validated for Western blot and immunohistochemistry on human samples.

The antibody is supplied as 100 µl of a 1 mg/ml stock in PBS with 0.1% sodium azide and 50% glycerol, an aqueous formulation that preserves activity for routine short-term handling. Polyclonal recognition across multiple epitopes of PRC1 supports detection of endogenous protein in lysates from proliferating cell lines, in formalin-fixed paraffin-embedded sections, and in cytological preparations of dividing cells.

Researchers investigating chromosome segregation, abscission, midbody organization, or PRC1 dysregulation in dividing cancer cells can use this reagent to probe the spatial and temporal localization of the protein through the cell cycle. The unconjugated format allows direct coupling to fluorophores, biotin, or reporter enzymes according to the secondary detection strategy chosen, and the product is intended for research use only.