Anti-PRAME Antibody

Raised in rabbit and affinity-purified against a recombinant human PRAME immunogen, this polyclonal antibody from Antibodies.com targets the PRAME (Preferentially Expressed Antigen in Melanoma) protein and detects the endogenous total PRAME level in human samples. It is supplied as an unconjugated reagent at a concentration of 1.0 mg/mL in a phosphate-buffered saline formulation (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol. The antibody is validated for Western blot (WB) and immunocytochemistry/immunofluorescence (ICC/IF) applications and is reactive with human samples. Each vial provides 50 µL of the polyclonal antibody, which should be stored short term at 4 °C upon receipt, then aliquoted and held at −20 °C with freeze/thaw cycles avoided to preserve activity. Because it is a polyclonal reagent raised in rabbit, the resulting immunoglobulin pool is not defined by a single isotype; instead, reactivity is determined by the affinity-purified antiserum against the PRAME immunogen. This product is intended for research use only and is not cleared for diagnostic or therapeutic applications. Researchers working on melanoma-associated antigens, cancer immunotherapy targets, or tumour antigen expression profiling will find the reagent well suited to detecting PRAME in cell-based and lysate-based assays.