Anti-PPP4R3B Antibody

Raised in rabbit as a polyclonal IgG reagent, this unconjugated primary antibody targets human PPP4R3B (Protein Phosphatase 4 Regulatory Subunit 3B), a regulatory subunit of the PP4 serine/threonine phosphatase complex implicated in the DNA damage response, cell cycle progression, and neuronal signaling. The antibody is supplied by Antibodies.com as a 100 µl volume and is validated for western blot detection of the human target across cell lysate and tissue-derived samples. Use it to probe for the ~85 kDa regulatory subunit in immunoblots of HEK293, HeLa, or neuronal cell extracts, where a clear band at the predicted molecular weight confirms expression of the PPP4R3B protein. The unconjugated format allows laboratories to pair it with their preferred reporter, secondary antibody, or beads for chemiluminescence, fluorescence, or HRP-based detection workflows. It supports investigations into PP4-mediated dephosphorylation pathways including ATM signaling, replication stress, and synaptic regulation where PPP4R3B has been functionally linked. For reliable performance in WB, store the IgG aliquot refrigerated at standard antibody storage conditions and minimize freeze-thaw cycles to preserve binding activity.