Anti-PPP2R5C Antibody

Raised in rabbit against the PPP2R5C protein, this polyclonal reagent from Antibodies.com targets the B56γ regulatory subunit of protein phosphatase 2A (PP2A). PP2A complexes incorporating this subunit contribute to dephosphorylation of substrates within MAPK and Wnt signaling cascades, and B56γ has been linked to regulation of cell cycle progression, apoptosis, and the DNA damage response in mammalian cells.

Validated for western blot (WB) and immunohistochemistry (IHC), the antibody cross-reacts with human, mouse, and rat samples, supporting comparative work across standard laboratory models. The product is supplied as 100 µl of a 1 mg/ml stock in PBS with 0.1% sodium azide and 50% glycerol. For long-term storage, keep the vial at -20 °C, ideally in small aliquots to limit freeze-thaw cycles and preserve binding activity.

Supplied in an unconjugated format, the antibody can be paired with a custom secondary antibody of the researcher's choice or used directly in chromogenic and fluorescence-based detection on fixed tissue sections and whole-cell lysate preparations.