Anti-PPP2R5A Antibody

Encoded by the PPP2R5A gene, the B56α regulatory subunit of protein phosphatase 2A can be detected in mouse samples using this rabbit polyclonal antibody from Antibodies.com. The unconjugated IgG reagent is supplied as a 100 µl vial, allowing laboratories to select their own HRP, biotin, or fluorescent secondary antibodies for western blot detection. The Primary Antibodies category listing reports reactivity against mouse samples.

B56α directs PP2A substrate specificity and has been studied in the contexts of mitotic checkpoint control, DNA damage response, and tau phosphorylation in neurons. Altered expression of PPP2R5A has been linked to neurodegenerative phenotypes in murine models, supporting application of this antibody in PP2A signalling research, cell cycle regulation studies, and characterisation of downstream phosphorylation events in mouse systems. Cross-reactivity with rat, human, or other species has not been independently confirmed for this particular lot, so the supplier datasheet should be consulted before extending the application beyond mouse samples.

For best results, aliquot the 100 µl stock upon first thaw to limit freeze-thaw cycles and store the working vial refrigerated for short-term use, with longer-term storage at -20 °C. This research use only reagent is intended for laboratory studies in vitro, including western blot-based characterisation of PP2A complexes and their downstream targets.