Anti-PPP2R1A Antibody

Raised in rabbit and affinity-purified as a polyclonal reagent, this unconjugated antibody recognizes the alpha isoform of the PP2A scaffolding subunit A (PPP2R1A), an approximately 65 kDa regulatory protein that forms the structural core of the serine/threonine phosphatase 2A complex. The antibody supplied by Antibodies.com is formulated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, and is provided as a 100 µl volume for routine immunodetection workflows.

Validated for Western blot and immunohistochemistry, the reagent detects endogenous PPP2R1A in human, mouse, and rat samples, supporting research into PP2A-dependent signaling in cell-cycle progression, apoptosis, and tumor biology where somatic PPP2R1A mutations are recurrently reported across multiple cancer types.

For best results, store at -20 °C in working aliquots, avoid repeated freeze-thaw cycles, and protect from light to preserve binding activity across blotting and staining experiments. The unconjugated format allows flexible pairing with secondary detection reagents chosen by the user.