Anti-PPP1R8 Antibody

This rabbit polyclonal IgG antibody targets PPP1R8, also known as NIPP1 (Nuclear Inhibitor of Protein Phosphatase 1), a nuclear regulatory subunit of protein phosphatase 1 that governs dephosphorylation events linked to RNA splicing, cell cycle progression, and transcription factor activity. Manufactured by Antibodies.com as an unconjugated primary antibody, the reagent is supplied at 200 µl and validated for western blot, immunohistochemistry, and immunofluorescence workflows. Researchers apply this reagent to map PP1-dependent signaling pathways in human, mouse, and rat samples, including studies of splicing factor regulation, mitotic exit, and chromatin-associated phosphatase activity. The polyclonal format provides broader epitope coverage than monoclonal alternatives, supporting consistent detection of endogenous PPP1R8 across lysate and tissue preparations. For storage, the antibody should be handled under refrigerated conditions to preserve IgG activity through repeated use in immunostaining and blotting protocols.