Anti-PPP1R15B Antibody

Raised in rabbit against the regulatory subunit PPP1R15B, this polyclonal antibody from Antibodies.com supports detection of the eIF2-alpha phosphatase complex that governs translational control during the integrated stress response. PPP1R15B counteracts stress-induced translational repression by recruiting protein phosphatase 1 to eIF2-alpha, making this reagent a useful marker for studies of ER stress recovery, translational regulation, and comparative analysis with the related regulatory subunit PPP1R15A.

The reagent is supplied as 100 µl of unconjugated antiserum and is validated for Western Blot and ELISA workflows against human samples. As a polyclonal reagent, it offers broader epitope coverage than monoclonal alternatives, which can be valuable when probing endogenous expression levels in cell lysates and tissue homogenates. Aliquoting upon arrival helps preserve activity across multiple experiments.

Each vial is intended for research use only and supports laboratory studies investigating the integrated stress response, ER-associated degradation pathways, or translational control mechanisms in human cell systems.