Anti-PPM1G Antibody

The Anti-PPM1G polyclonal reagent from Antibodies.com is a rabbit IgG antibody validated for western blot detection of protein phosphatase 1G (PPM1G), a Mg2+/Mn2+-dependent serine/threonine phosphatase concentrated in the nucleolus. PPM1G participates in pre-mRNA splicing complex assembly, ribosome biogenesis, and cell cycle progression through dephosphorylation of splicing factors and signaling intermediates. The antibody cross-reacts with both human and mouse PPM1G, enabling comparative immunoblotting studies of nucleolar phosphatase activity across cell lines, primary tissues, and experimental model systems. Each vial is supplied unconjugated at 100 µl, allowing researchers to pair the primary antibody with HRP, fluorophore, or biotin secondary detection chemistries according to their western blot workflow. The polyclonal antiserum recognizes multiple epitopes along the PPM1G polypeptide, supporting consistent band detection and reliable signal across independent immunoblotting replicates. Suitable for use alongside standard extraction and immunoprecipitation protocols, this Antibodies.com reagent is formatted for researchers investigating PP2C-family phosphatase signaling, splicing factor regulation, and nucleolar stress responses.