Anti-PPL Antibody

Raised in rabbit and affinity-purified as an unconjugated polyclonal reagent, this Antibodies.com primary antibody targets periplakin (PPL), a ~190 kDa cornified-envelope precursor also known as the 190 kDa paraneoplastic pemphigus antigen. The immunoglobulin is formulated at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, and is supplied as a 50 µl vial suitable for routine immunolabelling workflows. According to the supplier's validation data, the antibody has been tested in Western blot (WB), immunohistochemistry (IHC) and immunofluorescence (IF), and the published reactivity profile confirms robust detection in both human and mouse samples. The host species is rabbit, the clonality is polyclonal (IgG isotype), and the preparation is supplied unconjugated, giving users full flexibility to pair it with their own secondary detection reagents or label it directly. Shipped refrigerated on blue ice and intended for research use only, the reagent should be stored short term at 4 °C and, for longer term stability, aliquoted and kept at –20 °C with repeated freeze-thaw cycles avoided. The protein target, PPL, is a component of the epidermal cornified envelope and a recognized autoantigen in paraneoplastic pemphigus, making this reagent well suited to studies of keratinocyte differentiation, epithelial barrier biology, and autoantibody profiling. As listed in Antibodies.com's catalog of primary antibodies, the product offers a reliable, multi-application option for laboratories working on human and murine models of PPL expression.