Anti-PPIA Antibody

This unconjugated polyclonal reagent from Antibodies.com targets peptidylprolyl isomerase A (PPIA), the ~18 kDa cytosolic protein widely known as cyclophilin A. Raised in rabbit hosts and supplied at 100 µl per vial, the antibody is suited for western blot and immunohistochemistry workflows on human and mouse samples. Researchers commonly apply it to probe endogenous cyclophilin A levels in cell lysates, frozen tissue sections, and primary cell preparations, supporting studies of protein folding, inflammatory signaling, viral replication, and vascular stress biology.

Under reducing western blot conditions, the antibody recognizes the full-length cyclophilin A band; in immunohistochemistry, it produces cytoplasmic staining consistent with the protein's known localization. Refrigerate the vial at 4 °C for short-term use, then aliquot and freeze at -20 °C for longer retention to preserve binding activity across freeze-thaw cycles. Investigators working on chaperone biology, immunophilin function, or comparative CypA analysis in human and murine model systems will find this primary detection reagent a reliable addition to their antibody panel.