Anti-PPARA Antibody

This polyclonal antibody from Antibodies.com targets peroxisome proliferator-activated receptor alpha (PPARA), a ligand-activated nuclear transcription factor that regulates genes involved in fatty acid β-oxidation, lipid transport, and peroxisomal biogenesis. Raised in rabbit as an IgG preparation and supplied unconjugated in a 50 µL vial, the reagent is validated for Western blot detection of endogenous PPARA expression in human, mouse, and rat samples. Investigators in metabolic disease, hepatology, and cardiovascular research rely on PPARA profiling to study non-alcoholic fatty liver disease, dyslipidemia, insulin sensitivity, and the transcriptional response to fibrate-class drugs. The polyclonal format allows recognition of multiple epitopes on the receptor, which is useful for tracking full-length protein and major isoforms in lysates from liver, skeletal muscle, heart, kidney, and brown adipose tissue. Aliquoting is recommended to limit freeze-thaw cycles when the antibody is reserved for repeated Western blot experiments across multiple studies.