Anti-PP2A-Cα Antibody

Sourced from Antibodies.com, this rabbit polyclonal reagent targets the catalytic alpha subunit of protein phosphatase 2A and is supplied as a 50 µl liquid formulation at 1 mg/ml in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by epitope-specific affinity chromatography, using a synthetic peptide derived from human PP2A-Cα around the non-phosphorylation site of tyrosine307 as the immunogen, and the IgG preparation is provided unconjugated for flexible assay design. It is validated for Western blotting, immunohistochemistry, immunofluorescence and ELISA, and has been demonstrated on lysates from A549 and Jurkat cells by Western blot. Cross-reactivity has been confirmed against human, mouse and rat samples, making it suitable for a range of basic-research models studying PP2A signaling. For stability, the supplier recommends storage at -20 °C, under which conditions the product remains usable for up to one year; the reagent is intended for research use only and is not for diagnostic or therapeutic applications. Researchers working on serine/threonine phosphatase biology, cell-cycle regulation or related signaling pathways will appreciate the combination of polyclonal breadth, multi-application validation and the reliability expected of the Antibodies.com catalog.