Anti-POU4F3 Antibody

Raised in rabbit as a polyclonal IgG reagent, this unconjugated antibody targets the POU4F3 transcription factor and is validated for Western blot detection in human and rat samples. POU4F3 (POU domain class 4 transcription factor 3) is a key regulator of inner ear hair cell development and maintenance; loss-of-function mutations in the gene are linked to autosomal dominant non-syndromic hearing loss, also referenced as DFNA15. Researchers studying auditory neuroscience, cochlear hair cell biology, and hereditary deafness use this reagent to detect endogenous POU4F3 protein expression in tissue lysates and cultured cell lines. The product from Antibodies.com is supplied at 50 µl, sufficient for multiple immunoblot experiments, and is unconjugated to allow flexible selection of secondary labels and detection chemistries. It is intended for research use only, supporting investigations into hair cell regeneration, ototoxic injury responses, and the molecular pathways that govern sensory cell fate in the mammalian cochlea.