Anti-POU2F2 Antibody

POU2F2, also known as Oct-2, is a POU-homeodomain transcription factor that binds octamer DNA motifs to drive B-lymphocyte development and neuronal gene expression. From Antibodies.com, this rabbit polyclonal IgG reagent is raised against the human POU2F2 protein and cross-reacts with mouse and rat orthologs, supporting translational work that spans rodent disease models and human clinical samples. The unconjugated preparation is shipped as a 100 µl liquid aliquot in a single-use vial and is validated for Western blot analysis and immunohistochemistry on tissue sections.

Because the reagent is polyclonal, it recognizes multiple epitopes on the POU2F2 protein, which generally yields broader reactivity than monoclonal alternatives when denatured antigen is presented in blotting workflows. The rabbit host and IgG isotype pair cleanly with standard anti-rabbit secondary reagents, whether the lab chooses chromogenic DAB detection or fluorescent imaging. Groups studying lymphoid malignancies, germinal center B-cell maturation, Ig gene transcription, or neuronal transcription factor biology can deploy this antibody to confirm protein-level expression patterns initially identified by transcriptomic or ChIP-seq studies.

The product is intended for research use only and should be stored refrigerated in working aliquots to preserve activity across multiple experiments. Routine handling as a primary antibody in standard immunodetection platforms is supported, and the unconjugated format leaves fluorophore or enzyme choice to the researcher.