Anti-POLR2H Antibody

POLR2H encodes the eighth subunit of human RNA polymerase II, a core component of the transcription machinery responsible for synthesizing mRNA and most snRNAs. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against POLR2H and validated for Western blot, immunohistochemistry, and immunofluorescence workflows in human, mouse, and rat samples. The reagent is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a stabilizing cryoprotectant, packaged in a 100 µl vial.

It supports studies of RNA polymerase II assembly, transcription complex composition, and subunit-specific regulation of gene expression in cell and tissue lysates. The polyclonal format offers broader epitope coverage than a monoclonal reagent, while the unconjugated formulation lets researchers pair the primary with their preferred fluorophore- or enzyme-conjugated secondary antibody. For handling, store at -20 °C in working aliquots and limit freeze-thaw cycles to preserve binding activity across downstream assays.