Anti-POLR2H Antibody

This rabbit polyclonal IgG reagent from Antibodies.com recognizes POLR2H, the eighth subunit of RNA polymerase II. POLR2H, also called RPB8, is a shared subunit that sits at the assembly platform of the multi-subunit polymerase complex responsible for synthesizing messenger RNA and most small nuclear RNAs. The antibody supports research into transcription cycle regulation, RNA Pol II biogenesis, and the contribution of individual subunits to polymerase activity in human and mouse systems.

Validated for Western blot, the unconjugated antibody is supplied as a 200 µl volume and is compatible with standard chemiluminescent and fluorescent detection workflows that use anti-rabbit secondary reagents. Polyclonal recognition of multiple epitopes across POLR2H is helpful when probing full-length protein in whole-cell or nuclear lysates, and the unconjugated format lets users choose the label and detection chemistry that best fit their workflow.

For handling, aliquot the antibody into smaller working volumes on first use and store refrigerated to minimize freeze-thaw cycles; refer to the supplied data sheet for the exact recommended storage temperature and shelf life for this lot.