Anti-POLK Antibody

This rabbit polyclonal antibody from Antibodies.com targets POLK (DNA Polymerase Kappa), a Y-family translesion synthesis polymerase that supports DNA damage tolerance and error-prone replication past bulky lesions such as UV-induced cyclobutane pyrimidine dimers. The unconjugated IgG reagent is supplied at 50 µl and is validated for Western blot (WB) and immunofluorescence (IF) work across human, mouse, and rat samples, supporting studies of TLS pathway function, mutagenesis mechanisms, and polymerase expression in cell-based and tissue models. Researchers investigating genome stability, nucleotide excision repair interplay, or polymerase switching dynamics can apply the antibody to detect endogenous POLK by WB band analysis and by IF staining of fixed cells.