Anti-POLE3 Antibody

From the Antibodies.com catalogue, this rabbit polyclonal reagent is raised against POLE3 (DNA polymerase epsilon subunit 3) and is supplied at the 50 µl pack size as an unconjugated, affinity-purified IgG preparation at approximately 1.0 mg/mL. The immunogen is a recombinant human POLE3 protein, and the antibody is validated for Western blot detection of the endogenous POLE3 target in human and mouse samples, with additional immunofluorescence data referenced on the product page. The buffer formulation is phosphate-buffered saline at pH 7.4 (without Mg²⁺ and Ca²⁺) containing 150 mM sodium chloride, 0.02% sodium azide as preservative, and 50% glycerol for cryoprotection. The product is shipped on cold packs at 4 °C and should be aliquoted and stored long-term at –20 °C, with repeated freeze/thaw cycles avoided to preserve antibody activity. As a polyclonal host-rabbit reagent, it offers broader epitope coverage than monoclonal alternatives, making it well suited for chromatin, DNA replication, and DNA repair studies where subunit-level interrogation of the polymerase epsilon complex is required. The reagent is supplied by AFMS, offered for research use only, and is not cleared for diagnostic or therapeutic applications.