Anti-POLE3 Antibody

This unconjugated rabbit polyclonal IgG from Antibodies.com is raised against POLE3, the third subunit of the DNA polymerase epsilon complex (also known as CHRAC-17/p17). Supplied in a 50 µl volume, it detects the target in human and mouse samples by Western blot and immunofluorescence. Because POLE3 contributes to both the Pol ε replisome and the CHRAC chromatin accessibility complex, this reagent supports studies of DNA replication fidelity, nucleosome remodeling, and genome stability in cell biology and cancer research. The unconjugated format also gives flexibility to pair the primary with a user-selected secondary label for multiplex fluorescence imaging or chromogenic membrane detection.