Anti-POLDIP3 Antibody

Supplied by Antibodies.com as a 100 µl liquid aliquot, this rabbit polyclonal reagent targets human POLDIP3 (polymerase delta-interacting protein 3), a splicing- and replication-associated factor that joins the DNA polymerase delta complex, the spliceosome, and translation-initiation machinery in mammalian cells.

Raised in rabbit and purified as an unconjugated IgG, the antibody is validated for Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) on human and mouse samples. The reagent supports standard antibody-handling workflows, including aliquoting to limit freeze-thaw cycles during extended use.

Beyond routine detection, the reagent is deployed in co-immunoprecipitation workflows aimed at pulling down polymerase delta subunits, in chromatin fractionation studies of replication-fork components, and in fixed-cell imaging to localize POLDIP3 within nuclear speckles and nucleoplasm. Its dual recognition of human and mouse orthologs enables comparative work across cell-line panels and primary tissue sections, supporting studies of mRNA processing, DNA damage signaling, and the cellular response to replication stress.