Anti-POLD1 Antibody - Identical to Abcam (ab196561)

This rabbit polyclonal antibody from Antibodies.com targets POLD1 (DNA Polymerase Delta 1, Catalytic Subunit), the catalytic subunit of DNA polymerase delta that drives lagging-strand synthesis and participates in DNA replication and repair pathways.

The unconjugated IgG reagent is supplied as a 50 µl vial and is validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples. Each aliquot provides working volumes suitable for multiple experimental runs.

Researchers use this reagent to investigate replication stress, DNA damage response, and the role of POLD1 in tumorigenesis and progeroid syndromes. It is frequently applied in studies of genomic stability linked to MDPL syndrome (mandibular hypoplasia, deafness, progeroid features, and lipodystrophy), enabling detection of endogenous POLD1 expression in cell lines and tissue sections.