Anti-POLD1 Antibody - Identical to Abcam (ab196561)

This polyclonal reagent from Antibodies.com targets POLD1, the catalytic subunit of DNA polymerase delta, an essential enzyme complex responsible for leading-strand DNA synthesis and associated repair functions in eukaryotic cells. Formulated to match the Abcam reference ab196561, the antibody is a rabbit IgG preparation supplied as an unconjugated 100 µl volume, providing laboratories with a familiar alternative reagent for replication and repair studies.

Validated for Western blot, immunohistochemistry, and immunofluorescence workflows, the reagent shows reactivity against human, mouse, and rat samples, supporting cross-species investigations of DNA replication fidelity, genome stability, and DNA damage response pathways. Researchers examining Okazaki fragment processing, PCNA-mediated processivity, or mutational signatures associated with POLD1 deficiency can apply it to fixed tissue sections and cultured cell preparations alike.

As a polyclonal reagent, the antibody recognizes multiple epitopes across the target, which is useful when working with samples that may contain truncated variants or post-translationally modified forms of the polymerase. The unconjugated format is compatible with standard secondary antibody-based detection chemistries, including HRP, fluorescent dyes, and biotin-streptavidin approaches. The 100 µl volume supports multiple immunoblot and staining experiments in standard laboratory workflows.