Anti-PODXL Antibody

This rabbit polyclonal IgG primary antibody detects PODXL, a heavily sialylated transmembrane glycoprotein, in human, mouse, and rat samples. Antibodies.com supplies it as an unconjugated liquid antiserum at 200 µl for Western blot and immunofluorescence workflows.

In blotting, the reagent recognizes the high-molecular-weight PODXL signal associated with extensive O- and N-linked glycosylation. This is useful when comparing glomerular lysates or vascular endothelial preparations. Immunofluorescence labeling of the apical surface of kidney podocytes and capillary endothelium can support studies of podocyte morphology, glomerular injury models, filtration-barrier organization, and endothelial biology.

PODXL expression in primitive hematopoietic progenitors also makes the antibody relevant to stem and progenitor-cell characterization. Its involvement in cell adhesion, migration, and disease-associated tissue remodeling provides context for oncology research. The unconjugated format allows use with investigator-selected secondary reporters. Aliquot upon receipt, store frozen, and limit freeze-thaw cycles. For research use only.