Anti-PNP Antibody

Purine nucleoside phosphorylase (PNP) catalyzes the phosphorolysis of purine ribonucleosides in the salvage pathway and is relevant to studies of immunodeficiency and lymphoid malignancies. This rabbit polyclonal antibody from Antibodies.com detects endogenous PNP in human and mouse samples, validated for Western blot and immunoprecipitation workflows. The reagent is supplied as 100 µL of unconjugated IgG in a vial, supporting probing of cell lysates, tissue homogenates, and immunoprecipitated complexes.

Researchers investigating PNP deficiency, T-cell maturation, or nucleoside metabolism can apply this polyclonal reagent to characterize protein abundance and interactions across translational models. The unconjugated format permits flexible secondary antibody selection or custom conjugation, while the dual human-mouse reactivity profile supports comparative studies bridging murine disease models and patient-derived samples. Store refrigerated and aliquot upon arrival to minimize freeze-thaw cycles, preserving binding activity across multiple experimental runs.