Anti-PNOC Antibody

Raised in rabbit and affinity-purified against a recombinant human PNOC immunogen, this polyclonal reagent from Antibodies.com is supplied as an unconjugated, ready-to-use reagent at a working concentration of 1.0 mg/mL. The antibody is offered in a 50 µL aliquot and is validated for Western blot (WB) and immunocytochemistry/immunofluorescence (ICC/IF) applications, with reactivity confirmed against human samples. The host species is Rabbit, the clonality is Polyclonal, and the immunoglobulin class is IgG. The conjugate status is Unconjugated, allowing end users to couple the antibody to their preferred fluorophore or enzymatic label depending on the experimental design. PNOC, also known by the aliases OFQ and Prepronociceptin, encodes the precursor of nociceptin, a neuropeptide implicated in pain modulation, stress responses, and reward pathways, making this reagent relevant for neuroscience, pharmacology, and cell signalling research. The formulation consists of phosphate-buffered saline (without Mg²⁺ and Ca²⁺) at pH 7.4, supplemented with 150 mM NaCl, 0.02% sodium azide as a preservative, and 50% glycerol as a cryoprotectant. For optimal stability, the product is shipped at 4 °C and, upon receipt, should be aliquoted and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve binding activity. The Antibodies.com catalogue entry notes that the antibody detects the endogenous level of total PNOC, supporting its use in physiologically relevant expression studies. This primary antibody is intended for research use only and is not approved for diagnostic or therapeutic applications.