Anti-PNKP Antibody

The polyclonal reagent from Antibodies.com specifically targets human PNKP (Polynucleotide Kinase 3'-Phosphatase), a bifunctional DNA repair enzyme that phosphorylates 5'-hydroxyl termini and dephosphorylates 3'-phosphates during base excision repair and non-homologous end joining. Raised in Rabbit, this unconjugated polyclonal antibody is validated for Western Blot and Immunofluorescence workflows on human samples.

Each vial contains 100 µl of antiserum, ready to support research into DNA damage response, genomic stability, and neurological disease models such as MCSZ and Ataxia with Oculomotor Apraxia type 4, both linked to PNKP deficiency. The unconjugated format enables flexible detection chemistry selection, and the polyclonal nature provides multiple epitope recognition for robust signal in cell lysate and fixed-cell preparations.