Anti-PMS1 Antibody

Raised in rabbit and affinity-purified to detect endogenous levels of the DNA mismatch repair protein PMS1 (also known as MLH2 or PMSL1), this polyclonal reagent from Antibodies.com is supplied as an unconjugated IgG preparation in a 50 µl vial. The antibody is formulated at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, a buffer combination that preserves activity during routine bench handling and protects the protein through repeated freeze/thaw cycles. The host species is rabbit, the clonality is polyclonal, and the immunogen is a recombinant human PMS1 protein, ensuring reactivity with the native human target while cross-reacting with rat samples. Validated applications on the supplier datasheet cover Western Blot (WB) and Immunohistochemistry (IHC), making the reagent suitable both for confirming expression of PMS1 in cell or tissue lysates and for localising the protein in fixed sections. Because the antibody is unconjugated, it can be paired with a secondary reporter of the user's choice (HRP, fluorophore, or biotin), and it is shipped at 4 °C with the recommendation to aliquot upon arrival and store at -20 °C for continuous use. Researchers working on DNA mismatch repair, microsatellite instability, or hereditary cancer pathways will find this polyclonal PMS1 antibody a flexible primary reagent for both WB and IHC workflows.