Anti-PML Antibody

PML nuclear bodies organize a growing list of cellular processes, and the polyclonal anti-PML antibody from Antibodies.com provides a versatile tool for tracking the Promyelocytic Leukemia protein across multiple experimental platforms. Raised in rabbit and supplied as 100 µl of unconjugated antiserum, this reagent is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples and tissue sections.

The polyclonal format provides multi-epitope recognition, an advantage for detecting endogenous PML isoforms, SUMO-conjugated species, and post-translationally modified forms that monoclonal reagents may miss. In immunofluorescence, the antibody labels the characteristic speckled nuclear pattern of PML nuclear bodies, supporting studies in acute promyelocytic leukemia biology, DNA damage response, viral restriction pathways, and SUMO-dependent chromatin regulation. Intended for research use only, the unconjugated format allows direct integration with secondary antibody detection chemistries of the user's choice and with standard antigen-retrieval protocols in IHC.