Anti-PLTP Antibody

PLTP (Phospholipid Transfer Protein) is a key regulator of lipoprotein metabolism, mediating the transfer of phospholipids between HDL particles and other lipoprotein classes. This Rabbit polyclonal reagent from Antibodies.com targets PLTP and is validated for Western blot and immunohistochemistry workflows across human, mouse, and rat samples.

Supplied as a 100 µl liquid aliquot in unconjugated format, the antibody offers flexibility for both chromogenic and fluorescent detection chemistries. Its polyclonal clonality supports recognition of multiple epitopes on the PLTP molecule, which is advantageous when probing full-length protein or analyzing samples where epitope accessibility may vary because of post-translational modification or partial degradation.

For Western blot applications, the antibody is applied to tissue and cell lysates to compare PLTP expression levels in liver, brain, adipose, and macrophage sources. In immunohistochemistry, it enables localization studies in formalin-fixed paraffin-embedded sections, supporting investigations of PLTP distribution within tissue architecture. Researchers focused on HDL remodeling, reverse cholesterol transport, atherosclerosis pathogenesis, and metabolic disease models rely on this reagent for translational and cross-species comparison studies, particularly where differential regulation of PLTP is implicated in disease progression.