Anti-PLK1 (phospho T210) Antibody

This rabbit polyclonal antibody from Antibodies.com recognizes human PLK1 (Polo-Like Kinase 1) only when the kinase is phosphorylated at threonine 210, the activating mark located within its T-loop activation segment. Because T210 phosphorylation correlates directly with PLK1 catalytic activity, the reagent is used in mitosis and cell-cycle studies to follow kinase activation rather than total expression levels, and it is relevant to oncology research where PLK1 signaling is frequently dysregulated.

Supplied as 50 µL of unconjugated IgG in a vial, the antibody is validated for Western blot. The polyclonal format provides broader epitope coverage around the phospho-T210 region, which can be advantageous when tracking dynamic changes in kinase activation during mitotic entry, spindle assembly, or the DNA damage response.

The host species is rabbit, the isotype is IgG, and the conjugate is unconjugated, giving flexibility in secondary antibody choice and detection chemistry. Reactivity is restricted to human samples, and cross-reactivity with other species has not been established for this product.