Anti-Plexin-D1 Antibody

This unconjugated primary antibody from Antibodies.com is a rabbit polyclonal reagent raised against Plexin-D1, a transmembrane semaphorin receptor central to vascular patterning, endothelial cell migration, and axon guidance during development. Supplied in a 100 µl vial, the antiserum is validated for Western blot and immunofluorescence workflows on human samples, supporting studies of angiogenesis, tumor microenvironment biology, and neurovascular signaling.

Plexin-D1 (also known as PLXND1) belongs to the plexin family of single-pass transmembrane proteins that serve as principal receptors for class 3 semaphorins, transducing cues that remodel the actin cytoskeleton and direct cell motility. Researchers apply this antibody to map receptor localization in endothelial and neuronal tissue, monitor expression changes in disease models, and characterize pathways relevant to cancer progression and vascular remodeling. For routine use, refrigerate the vial; for longer storage, aliquot and freeze, protecting the reagent from repeated freeze-thaw cycles to maintain binding activity across downstream blotting and imaging applications.