Anti-PLEKHF2 Antibody

Raised in rabbit against the cytoplasmic PH-domain protein PLEKHF2, this polyclonal IgG reagent from Antibodies.com is supplied unconjugated in a 100 µl volume and validated for Western blot detection across human, mouse, and rat samples. PLEKHF2, also referred to as LL5β, binds the small GTPase ARL8B on late endosomes and lysosomes, supporting microtubule-dependent organelle positioning within cells.

Laboratories apply this antibody to investigate autophagy, endolysosomal trafficking, and cell migration dynamics. The polyclonal format offers broader epitope coverage than monoclonal alternatives, which is advantageous when probing proteins that exist as multiple isoforms or carry diverse post-translational modifications in cell lysates and tissue homogenates.

Aliquot upon receipt and store refrigerated; protect from light and avoid repeated freeze-thaw cycles to preserve antibody activity. Intended for research use only.