Anti-PLCG1 (phospho Y771) Antibody

PLCG1 (phospholipase C gamma 1) is a cytoplasmic enzyme that catalyzes the hydrolysis of PIP2 into IP3 and DAG, driving calcium release and PKC activation downstream of receptor tyrosine kinases. Phosphorylation at tyrosine 771 is a regulatory event tied to growth factor signaling and immune cell activation. This unconjugated rabbit IgG polyclonal reagent from Antibodies.com is raised against the phosphorylated Y771 epitope and is validated for western blot and immunofluorescence workflows. Supplied as a 200 µL vial, the antibody cross-reacts with human, mouse, and rat samples, supporting studies across cell line panels and primary tissue. Researchers commonly apply it to investigate EGFR- and PDGFR-driven pathways, T-cell receptor signaling, and oncogenic transformation in cancer models. Aliquot upon first use and store refrigerated to preserve phospho-specific reactivity across multiple freeze-thaw cycles.