Anti-PLCg1 (Ab-771) Antibody

This rabbit polyclonal antibody from Antibodies.com is raised against PLCg1 (Phospholipase C gamma 1) and is supplied as an unconjugated polyclonal preparation in a 100 µl vial, suitable for signal-transduction research. Affinity-purified from rabbit host serum, the reagent is provided ready for use in standard immunoassay workflows.

Validated for Western blot and immunohistochemistry, the antibody reacts with Human, Mouse, and Rat samples. PLCg1 is a phospholipase that converts PIP2 into the second messengers IP3 and DAG, driving calcium release and PKC activation downstream of activated receptor tyrosine kinases. Researchers studying EGFR, PDGF receptor, fibroblast growth factor receptor, or T-cell receptor signaling, as well as oncogenic transformation and chemotaxis, routinely use this reagent to monitor PLCg1 levels and pathway status in lysates and tissue sections.

Aliquot upon receipt and store at -20 degrees C in working volumes to limit freeze-thaw cycles. Each lot is quality-controlled by Western blot against cell lysates expressing endogenous PLCg1. This reagent is intended for research use only and is not validated for diagnostic or therapeutic applications.