Anti-platelet factor 4 variant 1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets platelet factor 4 variant 1 (PF4v1), a small chemokine (CXCL4 family) encoded by the PF4 gene and stored in the alpha granules of platelets, where it is released upon platelet activation. PF4v1 has been studied in the context of heparin-induced thrombocytopenia (HIT), megakaryocyte maturation, chemokine signalling through CXCR3, and vascular inflammation, making the reagent useful for cardiovascular, hematology, and thrombosis research programs.

The unconjugated antibody is raised in rabbit and validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples, allowing investigators to examine PF4v1 expression in platelet lysates, peripheral blood mononuclear cells, and formalin-fixed tissue sections. The polyclonal format provides recognition of multiple epitopes on the PF4v1 protein, which is helpful when probing variant isoforms or low-abundance chemokine pools. The reagent is supplied as a 100 µL vial for routine laboratory use and should be handled according to standard immunoglobulin storage recommendations to preserve activity across repeated freeze-thaw cycles.